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17-Jul-2017 03:21

Of the donors residing in earthquake affected regions (Kathmandu, Bhaktapur and Kavre), 3.2% (95% CI 2.7–4.0%) of donors were HEV Ig M positive, and two donors were positive for HEV antigen.

These HEV antigen positive individuals were also HEV Ig G positive (Table ], HEV is a topic of public health concern in developing countries.

In these instances, the missing data were subjected to multiple imputations prior to regression analyses.

Thus, in the absence of data from donors not responding to the study variables, potential bias in the inference could not be excluded.

Samples were tested for HEV Ig M, Ig G and antigen.

The proportion of donors positive for HEV Ig M or Ig G was calculated overall, and for each of the variables studied.

We therefore sought to estimate the rate of previous and recent HEV infection in Nepalese blood donors in the months following the large earthquakes.

In industrialised nations, HEV infections are associated with travel to countries endemic for HEV, however, autochthonous infections, mainly through zoonotic transmission, are increasingly being reported. Nepal has experienced a number of HEV outbreaks, and recent earthquakes resulted in predictions raising the risk of an HEV outbreak to very high.

This study aimed to measure HEV exposure in Nepalese blood donors after large earthquakes.

This study aimed to provide surveillance data about HEV in Nepal, determine the possible impact of the recent earthquakes through serological evidence of recent HEV exposure, and analyse variables as possible risk factors for exposure to HEV.

A total of 1,845 blood donors eligible to donate blood as per the criteria of the Central Blood Transfusion Service (CBTS), Nepal Red Cross Society (NRCS) were included in this study.

We therefore sought to estimate the rate of previous and recent HEV infection in Nepalese blood donors in the months following the large earthquakes.In industrialised nations, HEV infections are associated with travel to countries endemic for HEV, however, autochthonous infections, mainly through zoonotic transmission, are increasingly being reported. Nepal has experienced a number of HEV outbreaks, and recent earthquakes resulted in predictions raising the risk of an HEV outbreak to very high.This study aimed to measure HEV exposure in Nepalese blood donors after large earthquakes.This study aimed to provide surveillance data about HEV in Nepal, determine the possible impact of the recent earthquakes through serological evidence of recent HEV exposure, and analyse variables as possible risk factors for exposure to HEV.A total of 1,845 blood donors eligible to donate blood as per the criteria of the Central Blood Transfusion Service (CBTS), Nepal Red Cross Society (NRCS) were included in this study.Recent devastating earthquakes in Nepal could have facilitated an outbreak of HEV.